Hyperthermia induced by 3,4-methylenedioxymethamphetamine in unrestrained rhesus monkeys

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Hyperthermia induced by 3,4-methylenedioxymethamphetamine in unrestrained rhesus monkeys.

BACKGROUND Exposure to (+/-)3,4-methylenedioxymethamphetamine ((+/-)MDMA) results in lasting reductions of many markers for serotonin terminals in a range of species. In rodents, the severity of insult depends in large part on the generation of hyperthermia in the subject. (+/-)MDMA can produce either hyperthermia or hypothermia in rodents depending on the ambient temperature and these effects ...

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ژورنال

عنوان ژورنال: Drug and Alcohol Dependence

سال: 2006

ISSN: 0376-8716

DOI: 10.1016/j.drugalcdep.2005.09.013